Inform your doctor or pharmacist about all medications you are currently taking. Numerous drugs may interact with belumosudil, particularly:
Phenobarbital or other barbiturate medications
St. John’s wort
Antibiotics: rifabutin, rifampin, rifapentine
Cancer therapies: apalutamide, enzalutamide, mitotane
HIV/AIDS medications: efavirenz, nevirapine
Proton pump inhibitors for stomach acid: esomeprazole, lansoprazole, omeprazole (including brand names such as Nexium, Prevacid, Prilosec, Protonix, and others)
Anticonvulsants: carbamazepine, oxcarbazepine, phenytoin, primidone
Corticosteroids: dexamethasone, prednisone
This list is not exhaustive, and a wide range of other medications may influence the effects of belumosudil. These include prescription drugs, over-the-counter medications, vitamins, and herbal supplements. Not all potential drug-drug interactions have been listed herein.
