Dear Customers, Partners, and Relevant Parties:
BigBear Pharma's Capmatinib uses a light yellow coating powder for film coating. To further optimize supply chain management and achieve unified production management, our company has adjusted some production material suppliers, including the supplier of coating powder and the supplier of tablet compression tooling.
Because the coating powder manufacturer has been changed, light yellow coating powders produced by different manufacturers may differ to some extent in color, color difference control, and sources of raw and auxiliary materials. Therefore, the coating color of finished tablets may differ slightly from previous batches. At the same time, because the tablet compression tooling manufacturer has been changed, different tooling may have minor differences in edge shape, score lines, surface finish, and overall appearance. Therefore, the product appearance may vary to a certain extent compared with previous batches.
Product Information Involved:
Product Name: Capmatinib
Specification: 200 mg
Products manufactured after July 8, 2026
For illustrative purposes, actual tablet photos of Capmatinib before and after production are attached below:
(The above images are for reference only regarding appearance differences.)
Confirmation
Following evaluation and confirmation by our company's Quality Department, the above changes only involve differences in product appearance. They have not changed the product formulation composition, manufacturing process, quality standards, active ingredient content, dissolution behavior, stability, safety, or efficacy. The relevant products have all been tested in accordance with approved quality standards, and the results meet release requirements. They can be manufactured, sold, and used normally.
The purpose of this adjustment is to strengthen supply chain integration, achieve unified and standardized product manufacturing and quality management, and further ensure product quality stability and continuous supply capability.
Contact Information
If you have any questions or need further assistance, please contact our customer service or the relevant responsible person.
We sincerely apologize for any inconvenience this may cause and thank you for your understanding and support.
Hereby announced.
